Lindane

Lindane is an organochlorine chemical that has been used both as an agricultural insecticide and as a pharmaceutical treatment for headlice and scabies.

Lindane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA receptor-chloride channel complex at the picrotoxin binding site. In humans, lindane primarily affects the nervous system, liver and kidneys, and may be a carcinogen and/or endocrine disruptor.

When lindane is used in agriculture, an estimated 12-30% of it volatilizes into the atmosphere, where it is subject to long-range transport and can be deposited by rainfall.

 Lindane in soil can leach to surface and even ground water and can bioaccumulate in the food chain.

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